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Amyloid Oligomers Increase the Lifetime and Single Channel Conductance of Gramicidin Channels

✍ Scribed by Sokolov, Yuri; Milton, Saskia C.; Glabe, Charles G.; Hall, James E.


Book ID
121986613
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
49 KB
Volume
98
Category
Article
ISSN
0006-3495

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The effect of the pore-forming antibiotic gramicidin on pure lipid membranes is well characterized. We studied its action in protein-rich thylakoid membranes that contain less than 25% (wt/wt) acyl lipids. A transmembrane voltage was induced by flashing light, and its decay was measured and interpre