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Amyloid myopathy presenting with rhabdomyolysis: Evidence of complement activation

✍ Scribed by C. Rodolico; A. Mazzeo; A. Toscano; C. Pastura; D. Maimone; O. Musumeci; C. Musolino; G. Vita

Book ID: 116792713
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 187 KB
Volume: 16
Category: Article
ISSN: 0960-8966
DOI: 10.1016/j.nmd.2006.06.004

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We have recently reported a French family presenting with an X-linked vacuolated myopathy. Here we show that levels of complement components C5 and C9 are elevated in the serum of these patients. Moreover, antitrypsin activity is decreased in the serum of the patients. Taken with the deposition of m