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Amyloid Formation of a Protein in the Absence of Initial Unfolding and Destabilization of the Native State

✍ Scribed by Soldi, Gemma; Bemporad, Francesco; Torrassa, Silvia; Relini, Annalisa; Ramazzotti, Matteo; Taddei, Niccolò; Chiti, Fabrizio


Book ID
119919689
Publisher
Biophysical Society
Year
2005
Tongue
English
Weight
266 KB
Volume
89
Category
Article
ISSN
0006-3495

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## Abstract We compare folding trajectories of chymotrypsin inhibitor (CI2) using a dynamic Monte Carlo scheme with Go‐type potentials. The model considers the four backbone atoms of each residue and a sphere centered around C^β^ the diameter of which is chosen according to the type of the side gro