## Abstract ## BACKGROUND Current adjuvant hormone therapy in postmenopausal women with breast cancer is debatable between upfront aromatase inhibitors (AIs) and sequential treatment with tamoxifen. A major concern is the higher rate of early recurrences observed with sequential treatment. The aut
✦ LIBER ✦
Amplification ofESR1may predict resistance to adjuvant tamoxifen in postmenopausal patients with hormone receptor positive breast cancer
✍ Scribed by Kirsten Vang Nielsen; Bent Ejlertsen; Sven Müller; Susanne Møller; Birgitte B. Rasmussen; Eva Balslev; Anne-Vibeke Lænkholm; Peer Christiansen; Henning T. Mouridsen
- Publisher
- Springer US
- Year
- 2010
- Tongue
- English
- Weight
- 585 KB
- Volume
- 127
- Category
- Article
- ISSN
- 0167-6806
No coin nor oath required. For personal study only.
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## Abstract ## BACKGROUND The Pre‐Operative “Arimidex” Compared to Tamoxifen (PROACT) study was a randomized, multicenter study comparing anastrozole with tamoxifen as a preoperative treatment of postmenopausal women with large, operable (T2/3, N0‐2, M0), or potentially operable (T4b, N0‐2, M0) br
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