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Amplification of the mdm2 gene, but not expression of splice variants of mdm2 mrna, is associated with prognosis in soft tissue sarcoma

✍ Scribed by Frank Bartel; Axel Meye; Peter Würl; Matthias Kappler; Matthias Bache; Christine Lautenschläger; Ulrich Grünbaum; Hannelore Schmidt; Helge Taubert


Publisher
John Wiley and Sons
Year
2001
Tongue
French
Weight
149 KB
Volume
95
Category
Article
ISSN
0020-7136

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While platelet-derived growth factor, PDGF, is not regularly expressed in mesenchymal tissues, PDGF B mRNA is often found in tumors derived from these tissues. PDGF B protein is also present, but the protein levels in individual tumors do not appear to correlate well with those of the mRNA. PDGF B i