Amplification of diastereoselectivity by cyclodextrins in the copper-mediated cleavages of methylphosphonamidothioates

✍ Scribed by Robert A Moss; Jingzhi Tian

• Book ID: 104253552
• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 99 KB
• Volume: 44
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(03)00782-2

✦ Synopsis

Cu-mediated cleavage, coupled with diastereoselective binding and orientational preferences supplied by g-cyclodextrin, lead to substantial kinetic diastereoselectivity between phosphonamidothioate diastereomers.