Amplification and loss of repeat units of the human minisatellite MS1 integrated in chromosome III of a haploid yeast strain

Chemically induced changes in the spectr

Chemically induced changes in the spectrum of amplifications of the human minisatellite MS1 integrated in chromosome III of a haploid yeast strain

✍ Agurell, Eva ;Cederberg, Hakan ;Hedenskog, Mona ;Rannug, Ulf 📂 Article 📅 1994 🏛 Springer 🌐 English ⚖ 873 KB

To study chemically induced DNA amplifications we used the haploid Saccharomyces cerevisiae strain TR(MS1)-I carrying an integrated chromosomal copy of the human minisatellite, MS1. Chemicals with different mechanisms of action were tested in this strain: methyl methanesulphonate, ethylene oxide (EO