Previous studies have established that colon carcinoma cells secrete several polypeptide growth factors, including TGF-dEGF and TGF-B, suggesting that these and related molecules function in an autocrindparacrine fashion to modulate tumor-cell growth. To investigate this possibility, we have studied
Amplification and expression of the TGF-α, EGF receptor and c-mycgenes in four human oesophageal squamous cell carcinoma lines
✍ Scribed by Gregory J. Jones; Nina S. Heiss; Robin B. Veale; Alan L. Thornley
- Book ID
- 112486774
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 785 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0144-8463
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
A number of studies suggest that an inverse correlation exists between the epidermal growth factor-receptor and the estrogen receptor expression in primary human breast carcinoma as well as in established human breast carcinoma cell lines. Recent studies suggest that the epidermal growth factor-rece
Human A431 carcinoma cell line is known to have 30 fold amplified epidermal growth factor receptor (EGF-R) gene. We have studied the effect of steroid hormone dexamethasone (DEX) and protein synthesis inhibitor cycloheximide (CHX) on the expression of EGF-R gene in this cell line. DEX treatment and
## Abstract It has been previously demonstrated that human carcinomas express interleukin‐2 receptor (IL‐2R) α, β, and γ chains. The β and γ chains of IL‐2R have intermediate binding affinity for IL‐2 and are responsible for the intracellular signaling cascades after IL‐2 stimulation. IL‐2Rα lacks