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Ampicillin micronization by supercritical assisted atomization

✍ Scribed by E. Reverchon; G. Della Porta; A. Spada


Book ID
111768984
Publisher
Pharmaceutical Press
Year
2003
Tongue
English
Weight
666 KB
Volume
55
Category
Article
ISSN
2042-7158

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## Abstract Supercritical Assisted Atomization (SAA) has been used to produce lysozyme microparticles. Lysozyme has been micronized using water, buffered water at pH 6.2 and water–ethanol mixtures at different volume percentages. Precipitated lysozyme particles were spherical, with a narrow particl

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## Abstract The supercritical assisted atomization (SAA) was proposed as a new technique to produce composite microparticles for drug controlled release. Ampicillin trihydrate and chitosan were selected as model drug and carrier, respectively, and 1% v/v acetic acid aqueous solution was used as sol