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Amphotericin B: Relationship between nephrotoxicity and inhibition of PKA and p38 MAPK signaling pathways

✍ Scribed by França, F.D.; Tagliati, C.A.; Chaves, M.M.

Book ID: 121265121
Publisher: Elsevier Science
Year: 2013
Tongue: English
Weight: 73 KB
Volume: 221
Category: Article
ISSN: 0378-4274
DOI: 10.1016/j.toxlet.2013.05.275

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## Abstract Pseudolaric acid B (PAB) is a major bioactive component of the medicinal plant __Pseudolarix kaempferi__. Traditional medicine practitioners in Asia have been using the roots of this plant to treat inflammatory and microbial skin diseases for centuries. In the current study, in vitro im