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Amphotericin B lipid complex

✍ Scribed by Brasil, Patrícia; Costa, Anielle P; Longo, Cecilia L; da Silva, Sidnei; Ferreira-da-Cruz, Maria F; Daniel-Ribeiro, Cláudio Tadeu


Book ID
121599491
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2013
Weight
128 KB
Volume
1479
Category
Article
ISSN
0114-9954

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The goal of this study was to determine the effect of apolipoproteins on Amphotericin B lipid complex (ABLC). We report that incubation of ABLC with recombinant human apolipoprotein A-I (apoA-I) induces solubilization of ABLC by transforming the micron sized phospholipid/AMB assemblies into discrete