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Amphidinolide B: Asymmetric Synthesis of a C 7 −C 20 Synthon

✍ Scribed by Gopalarathnam, Apsara; Nelson, Scott G.

No coin nor oath required. For personal study only.

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Efficient synthesis of the C7-C20 subuni

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The C-1 ~ C-13 segment (2) of amphidinolide B (1), a potent cytotoxic 26-membered macrolide, has been synthesized.

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