Amphibian metamorphosis assay

✍ Scribed by OECD

Publisher: OECD Publishing
Year: 2009
Tongue: English
Leaves: 33
Series: OECD Guidelines for the Testing of Chemicals. Section 2, Effects on Biotic Systems.
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

This Test Guideline describes an amphibian metamorphosis assay intended to screen substances which may interfere with the normal functioning of the hypothalamo-pituitary-thyroid axis. The assay was validated with the species Xenopus laevis, which is recommended for use in the Guideline. The assay uses three test chemical concentrations and the necessary controls, including a carrier control if necessary. The assay Read more...

✦ Subjects

Amphibians -- Metamorphosis;Chemical tests and reagents;Amphibians -- Metamorphosis

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