Amphibian metamorphosis: An immunologic opportunity!

✍ Scribed by Laurens N. Ruben; Richard H. Clothier; Michael Balls; John D. Horton

• Book ID: 102761560
• Publisher: John Wiley and Sons
• Year: 1989
• Tongue: English
• Weight: 697 KB
• Volume: 10
• Category: Article
• ISSN: 0265-9247
• DOI: 10.1002/bies.950100103

✦ Synopsis

Anuran amphibian metamorphosis is an immunologically interesting period. For the investigator, it provides an unusual opportunity for analyzing both humoral regulation of the immune response and the development and maintenance of sewtolerance. Some of the questions one can ask are : Why don't immunocompetent larvae destroy antigenically disparate adult cells as they diferentiate within them during metamorphosis? Do the dramatic hormonal changes occurring during this period regulute immunological function? How do animals in metamophorsis protect themselves from their immunologically hostile environment?