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AMP Kinase Activation Mitigates Dopaminergic Dysfunction and Mitochondrial Abnormalities in Drosophila Models of Parkinson's Disease

✍ Scribed by Ng, C.-H.; Guan, M. S. H.; Koh, C.; Ouyang, X.; Yu, F.; Tan, E.-K.; O'Neill, S. P.; Zhang, X.; Chung, J.; Lim, K.-L.

Book ID
120009400
Publisher
Society for Neuroscience
Year
2012
Tongue
English
Weight
1010 KB
Volume
32
Category
Article
ISSN
0270-6474

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## Abstract Nicotinamide, the principal form of niacin (vitamin B3), has been proposed to be neuroprotective in Parkinson's disease. However, the effects and mechanisms of nicotinamide on motor function in animals and on mitochondrial function in cellular systems have not been well studied. We hypo