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AMP-activated protein kinase attenuates Wnt/β-catenin signaling in human osteoblastic Saos-2 cells

✍ Scribed by Tomozumi Takatani; Masanori Minagawa; Rieko Takatani; Kaori Kinoshita; Yoichi Kohno

Book ID
116735001
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
461 KB
Volume
339
Category
Article
ISSN
0303-7207

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## Abstract Although the intermittent administration of PTH is known to stimulate the bone formation, the underlying mechanisms are not fully understood. Here we investigated the crosstalk between PTH/cAMP signaling and canonical Wnt signaling using the human osteoblastic cell line Saos‐2. Treatmen