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Amounts and variation in grapefruit juice of the main components causing grapefruit–drug interaction

✍ Scribed by Katsuyuki Fukuda; Lianqing Guo; Noriko Ohashi; Masayoshi Yoshikawa; Yasushi Yamazoe


Book ID
108447567
Publisher
Elsevier Science
Year
2000
Weight
210 KB
Volume
741
Category
Article
ISSN
0378-4347

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To investigate the potential interaction between selected ingredients of grapefruit juice and, the transport of talinolol, a P-gp substrate, across Caco-2 cells monolayers was determined in the absence and presence of distinct concentrations of grapefruit juice, bergamottin, 6 0 ,7 0 -dihydroxyberga