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Amodiaquine retains efficacy against uncomplicated falciparum malaria in areas of chloroquine resistance,

✍ Scribed by Innes, Carmen

Book ID: 120871189
Publisher: Adis International Limited (now part of Wolters Kluwer Health)
Year: 2000
Weight: 133 KB
Volume: &NA;
Category: Article
ISSN: 1173-8324
DOI: 10.2165/00128413-200012220-00031

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Chlorpheniramine, a histamine HI receptor antagonist, reverses chloroquine resistance in Plasmodium falciaarum in vitro. However. the clinical sianificance of this remains unclear. We have evaluated the efficacv of chloroquine and a chloroquine-chlorbheniramine combination in 112 consecutive childre