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Amniotic membrane immobilized poly(vinyl alcohol) hybrid polymer as an artificial cornea scaffold that supports a stratified and differentiated corneal epithelium

✍ Scribed by Yuichi Uchino; Shigeto Shimmura; Hideyuki Miyashita; Tetsushi Taguchi; Hisatoshi Kobayashi; Jun Shimazaki; Junzo Tanaka; Kazuo Tsubota

Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 244 KB
Volume: 81B
Category: Article
ISSN: 1552-4973
DOI: 10.1002/jbm.b.30654

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Amniotic membrane immobilized poly(vinyl

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## Abstract Poly(vinyl alcohol) (PVA) is a biocompatible, transparent hydrogel with physical strength that makes it promising as a material for an artificial cornea. In our previous study, type I collagen was immobilized onto PVA (PVA‐COL) as a possible artificial cornea scaffold that can sustain a

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## Abstract The cornea is a transparent tissue of the eye, which is responsible for the refraction of incoming light. Both biological corneal equivalents and synthetic keratoprostheses have been developed to replace donor tissue as a means to restore vision. However, both designs have drawbacks in