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Amnion rupture sequence in previable fetuses

โœ Scribed by Kalousek, D. K. ;Bamforth, S. ;Opitz, John M. ;Reynolds, James F.


Book ID
102699800
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
668 KB
Volume
31
Category
Article
ISSN
0148-7299

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โœฆ Synopsis


Amnion rupture sequence is considered an uncommon, sporadic condition among liveborn infants. We have examined 1,010 previable fetuses (9-20 weeks developmental age) to determine the incidence and nature of amnion rupture sequence at this stage of development. We found 18 affected fetuses (15 spontaneous and 3 induced abortions) with the incidence of 1:56. Eleven fetuses had limb constrictions and amputations only; 7 fetuses also had nonlimb involvement, including disruptions of the craniofacial region mimicking encephalocele, unusual facial clefts, and abdominal defects. In 6 pregnancies, constrictions of the umbilical cord by amniotic bands were the cause of fetal intrauterine death.


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## Abstract **BACKGROUND:** Amniotic bands can cause disruption of the cranial end of the developing fetus, leading in some cases to a neural tube closure defect. Although recurrence for unaffected parents of an affected child with a defect in which the neural tube closed normally but was subsequen