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Ammonia Excretion by Mammalian Lung

✍ Scribed by ROBIN, E. D.; TRAVIS, D. M.; BROMBERG, P. A.; FORKNER, C. E.; TYLER, J. M.

Book ID
121164880
Publisher
American Association for the Advancement of Science
Year
1959
Tongue
English
Weight
510 KB
Volume
129
Category
Article
ISSN
0036-8075

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## Abstract An adenosine kinaseless (AK^βˆ’^) mutant of the mouse fibroblast line 3T6 has been obtained in cell culture by evolution of resistance to 6‐thio‐methylpurine ribonucleoside and tubercidin. The mutant excretes purines (xanthine and hypoxanthine) into the culture medium. Human or mouse cell