✦ LIBER ✦
Ammonia chemical ionization tandem mass spectrometry in structure determination of alkaloids. I. Pyrrolidines, piperidines, decahydroquinolines, pyrrolizidines, indolizidines, quinolizidines and an azabicyclo[5.3.0]decane
✍ Scribed by H. Martin Garraffo; Thomas F. Spande; Tappey H. Jones; John W. Daly
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 157 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0951-4198
No coin nor oath required. For personal study only.
✦ Synopsis
CI-MS/MS of alkaloids with ammonia reagent gas and collision-induced dissociation provides unique structural information for certain mono-and bi-cyclic alkaloids. This technique was applied
to solve the structures of 195C, a 4,6-disubstituted quinolizidine alkaloid found in frog skin and an ant, and 275A, a novel 3,5-disubstituted azabicyclo[5.3.0]decane found in frog skin.