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Aminophosphordichloridite: A new phosphorylating reagent for one-pot synthesis of 3'-5'- or 2'-5'-linked diribonucleotide having defined sequence

✍ Scribed by Takeo Shimidzu; Kazushige Yamana; Seiichiro Maikuma

Publisher: Elsevier Science
Year: 1984
Tongue: French
Weight: 236 KB
Volume: 25
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)81405-2

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✦ Synopsis

3'-5'-or 2'-5'-linked diribonucleotides having definite sequences have been synthesized by an one-flask procedure utilizing the cyclic phosphorylation of the cis-glycol in the ribonucleosides with aminophosphordichloridites.

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