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Aminohexanoic hydroxamate is a potent inducer of the differentiation of mouse neuroblastoma cells

✍ Scribed by Jiebo Lu; Zong Ping Chen; Yong Ping Yan; Spencer Knapp; Harvey Schugar; Kuang Yu Chen


Book ID
117466659
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
402 KB
Volume
160
Category
Article
ISSN
0304-3835

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Neuroblastoma cells are used as a model system to study neuronal differentiation. Here we describe the induction of morphological differentiation of mouse neuroblastoma Neuro 2a (N2a) cells by treatments with either chemical inhibitors of cyclin-dependent kinases or lithium, which inhibits glycogen