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Aminocadambines A and B, two novel indole alkaloids from Neolamarckia cadamba

✍ Scribed by Ling-Li Liu; Ying-Tong Di; Qiang Zhang; Xin Fang; Feng Zhu; Dong-Lin Chen; Xiao-Jiang Hao; Hong-Ping He

Book ID: 104098211
Publisher: Elsevier Science
Year: 2010
Tongue: French
Weight: 494 KB
Volume: 51
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2010.08.030

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✦ Synopsis

Two novel monoterpenoid indole alkaloids, aminocadambines A (1) and B (2), characterized by tetrahydrofuran and 1,2,3,4-tetrahydropyridine rings, were isolated from the leaves of Neolamarckia cadamba. Their structures were elucidated on the basis of spectroscopic and computational methods. The absolute configuration of 1 was established by CD analysis. A plausible biosynthetic pathway for 1 and 2 is proposed.

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