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Amino-terminal fragment of urokinase-type plasminogen activator inhibits its plasminogen activation

✍ Scribed by Ziyong Sun; Pei-Xiang Zhang; Ping Wang; Victor Gurewich; Hai-Yan Shen; Jian-Ning Liu


Book ID
117257280
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
182 KB
Volume
106
Category
Article
ISSN
0049-3848

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Urokinase-type plasminogen activator inh
✍ H. Michael Tucker; Muthoni Kihiko-Ehmann; Steven Estus πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 335 KB πŸ‘ 1 views

## Abstract Amyloid‐β (AΞ²) appears central to Alzheimer's disease (AD), aggregates spontaneously, and is neurotoxic to neurons in vitro. Recently, several groups reported a familial AD locus on chromosome 10. Here, we note that urokinase‐type plasminogen activator (uPA) is located within this locus