Amino acids in the synthesis of heterocyclic compounds. Transformations of thiazolones into imidazole derivatives
✍ Scribed by Anton Copar; Branko Stanovnik; Miha Tisler
- Book ID
- 112130252
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1992
- Tongue
- English
- Weight
- 390 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0022-152X
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## Abstract The direct annelation reaction of 4‐substituted 2‐amino‐l‐benzylideneamino‐1__H__‐imidazoles (**1**) or 2‐amino‐1‐isopropylideneamino‐1__H__‐imidazole (**8**) with ethoxymethylenemalononitrile (**I**) gave successfully bicyclic imidazo[1,2‐__a__]pyrimidine compounds **2** and **9** in h
## Abstract A series of new optically active 1__H__‐imidazole 3‐oxides **5** with a substituted acetate group at N(1) as the chiral unit were prepared by the reaction of __α__‐(hydroxyimino) ketones, __α__‐amino acid methyl esters, and formaldehyde. In an analogous reaction, ethyl 2‐(hydroxyimino)‐