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Amino acids in the syntheses of heterocyclic systems: Syntheses and radiostability of novel biologically active triazoles containing the sulfonamide moiety

✍ Scribed by A. M. Sh. El-Sharief; M. M. Ghorab; M. S. A. El-Gaby; Sh. I. Mohamed; Y. A. Ammar

Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
236 KB
Volume
13
Category
Article
ISSN
1042-7163

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✦ Synopsis

Abstract

A number of novel triazoles 2a–f, 4, 9, 10, 12, 15; triazolothiadiazoles 6, 8, 11, 16; triazolothiadiazine 5; and triazolotriazine 14 were synthesized and characterized by elemental analyses and spectral data. Six of the compounds showed antifungal activity compared with the fungicide Mycostatine. Radiosterilization of the biologically active compounds 4, 8, 9b, and 10 in the dry state may prove to be applicable at the sterile dose 25 kGy. © 2002 Wiley Periodicals, Inc. Heteroatom Chem 13:316–323, 2002; Published online in Wiley Interscience (www.interscience.wiley.com). DOI 10.1002/hc.10037

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