Amino Acid Sequences Surrounding the cAMP-Dependent and Calcium/Calmodulin-Dependent Phosphorylation Sites in Rat and Bovine Synapsin I

Activators of protein kinase C increase

Activators of protein kinase C increase the phosphorylation of the synapsins at sites phosphorylated by cAMP-dependent and Ca2+/calmodulin-dependent protein kinases in the rat hippocampal slice

✍ Michael D. Browning; Ellen M. Dudek 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 950 KB

Previous studies have shown that activators of protein kinase C (C kinase) produce synaptic potentiation in the hippocampus. For example, the C kinase activator phorbol dibutyrate has been shown to increase transmitter release in the hippocampus. In addition, a role for C kinase in long-term potenti