Amino acid propensities for secondary structures are influenced by the protein structural class
β Scribed by Susan Costantini; Giovanni Colonna; Angelo M. Facchiano
- Book ID
- 116292352
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 261 KB
- Volume
- 342
- Category
- Article
- ISSN
- 0006-291X
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π SIMILAR VOLUMES
Knowledge of amino acid composition, alone, is verified here to be sufficient for recognizing the structural class, alpha, beta, alpha + beta, or alpha/beta of a given protein with an accuracy of 81%. This is supported by results from exhaustive enumerations of all conformations for all sequences of
The multidimensional statistical technique of discriminant analysis is used to allocate amino acid sequences to one of four secondary structural classes: high a content, high / 3 content, mixed a and @, low content of ordered structure. Discrimination is based on four attributes: estimates of percen