Two MBC-resistant mutants of Neurospora crassa, F914 and F939, were sensitive to diethofencarb at a concentration of 0.1 gg/ml, while the wild-type strain and other MBC-resistant mutants showed resistance to diethofencarb at a concentration of 100 ~tg/ml. Genetic analysis suggested that the mutation
✦ LIBER ✦
Amino-acid alterations in theβ-tubilin gene ofNeurospora crassathat confer resistance to carbendazim and diethofencarb
✍ Scribed by Makoto Fujimura; Takashi Kamakura; Hirokazu Inoue; Isamu Yamaguchi
- Publisher
- Springer-Verlag
- Year
- 1994
- Tongue
- English
- Weight
- 478 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0172-8083
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## Abstract We report the cloning and sequencing of 18 mutant alleles of the __benA__, β‐tubulin gene of __Aspergillus nidulans__ that confer resistance to the benzimidazole antifungal, antimicrotubule compounds benomyl, carbendazim, nocodazole, and thia‐bendazole. In 12 cases, amino acid 6 was cha