Ciclosporin metabolite pattern in blood
โ
J. S. Bleck; H. J. Schlitt; U. Christians; R. Schottmann; C. Thiesemann; S. Stro
๐
Article
๐
1991
๐
Springer
๐
English
โ 483 KB
Ciclosporin, an immunosuppressant, is metabolized by the liver cytochrome P450 system. Changes in the pattern of its metabolites in blood and urine in patients with disturbed liver function have been studied. Forty seven kidney graft patients receiving 2.9 mg/kg/d ciclosporin b.i.d., and no addition