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Amine-surface-modified superparamagnetic iron oxide nanoparticles interfere with differentiation of human mesenchymal stem cells

โœ Scribed by You-Kang Chang; Yu-Peng Liu; Jennifer H. Ho; Shu-Ching Hsu; Oscar K. Lee


Book ID
112134336
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
579 KB
Volume
30
Category
Article
ISSN
0736-0266

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Superparamagnetic iron oxide (SPIO) nanoparticles are very useful in cell imaging; meanwhile, however, biosafety concerns associated with their use, especially on therapeutic stem cells, have arisen. Most studies of biosafety issues focus on whether the nanoparticles have deleterious effects. Here,