Amiloride: an inhibitor of regulatory volume decrease in rat pheochromocytome cultured cells

Biphasic rises in cytosolic free Ca2+in

Biphasic rises in cytosolic free Ca2+in association with activation of K+and Cl−conductance during the regulatory volume decrease in cultured human epithelial cells

✍ Akihiro Hazama; Yasunobu Okada 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 535 KB

During exposure to a hypotonic solution (55% osmolarity), cultured human epithelial (Intestine 407) cells exhibit a regulatory volume decrease after osmotic swelling. This process is known to involve parallel activation of volume-regulatory K + and C1-conductances. Biphasic increase in the cytosolic