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Amifostine cytotoxicity and induction of apoptosis in a human myelodysplastic cell line

✍ Scribed by Iole Ribizzi; James W Darnowski; Frederick A Goulette; Mario Roberto Sertoli; Paul Calabresi

Book ID
114118836
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
152 KB
Volume
24
Category
Article
ISSN
0145-2126

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## Abstract A series of geiparvarin analogues modified on the unsaturated alkenyloxy bridge, where a H‐atom replaced the 3′‐Me group, were synthesized and evaluated against a panel of human tumor cell lines __in vitro.__ These compounds demonstrated a stronger increase in growth inhibitory activity