## Abstract We wish to study the effects of genetic and environmental factors on disease risk, using data from families ascertained because they contain multiple cases of the disease. To do so, we must account for the way participants were ascertained, and for withinβfamily correlations in both dis
Amendments and Corrections: Logistic Regression of Family Data From Case- Control Studies
β Scribed by Alice S. Whittemore
- Book ID
- 124289804
- Publisher
- Oxford University Press
- Year
- 1997
- Tongue
- English
- Weight
- 219 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0006-3444
- DOI
- 10.2307/2337673
No coin nor oath required. For personal study only.
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## Abstract A complex web of geneβgene and geneβenvironment interactions likely underlies lateβonset disease development. We compared conditional logistic regression (CLR) and generalized estimating equations (GEE) in modeling such interactions in pedigrees with missing parents. Using the simulatio
## A batract A number of statistics have recently been proposed t o asssess the fit of the multiple logistic regression model in both prospective and retrospective studies involving two independent samples as well as in cross sectional studies. These statistics are not appropriate for assessing fi