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Ameliorative effects of a cognitive enhancer, T-588, on place learning deficits induced by transient forebrain ischemia in rats

โœ Scribed by Yasushi Nakada; Ryoi Tamura; Jun-Ichi Kuriwaki; Tatsuo Kimura; Teruko Uwano; Hisao Nishijo; Taketoshi Ono

Book ID
117197581
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
485 KB
Volume
74
Category
Article
ISSN
0031-9384

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## Abstract Alzheimer's disease (AD) is a neurodegenerative disease characterized by cognitive decline due to neuronal loss and neural network dysfunction. It has been postulated that progressive neuronal loss in AD is consequence of the neurotoxic properties of the amyloidโ€ฮฒ peptide (Aฮฒ). In the p