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Amelioration of prolidase deficiency in fibroblasts using adenovirus mediated gene transfer

✍ Scribed by Kumiko Ikeda; Jun Tohyama; Seiichi Tsujino; Kahei Sato; Takashi Oono; Jirô Arata; Fumio Endo; Norio Sakuragawa

Book ID
110676780
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
628 KB
Volume
42
Category
Article
ISSN
1435-232X

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## Abstract ## Objective The phosphatidylinositol 3‐kinase (PI 3‐kinase)/Akt pathway is known to be activated in rheumatoid arthritis (RA) synovial tissue, which impacts cell growth, proliferation, survival, and migration. Phosphatase and tensin homolog deleted from chromosome 10 (PTEN) functions