Ambulatory blood pressure monitoring in elderly hypertensives treated with the new calcium antagonist, nilvadipine
✍ Scribed by T. Tsuchihashi; A. Tsukashima; K. Matsumura; I. Abe; M. Tominaga; Y. Nakao; K. Kobayashi; M. Fujishima
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 210 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0031-6970
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✦ Synopsis
A newly developed calcium antagonist, nilvadipine, was administered to 7 hypertensive patients aged 75.6 y. Nilvadipine 4 mg b.d. decreased the average 24-h blood pressure significantly from 169/89 mmHg to 152/81 mmHg after 7 to 14 days without any change in the pulse rate. The circadian patterns of blood pressure and pulse rate were not affected by nilvadipine. Although the present study was a preliminary one done over a short period in a small number of patients, the results suggest that nilvadipine exerts an antihypertensive effect without altering the circadian pattern or the variability of blood pressure in elderly hypertensive patients.