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Ambroxol interferes with Pseudomonas aeruginosa quorum sensing

โœ Scribed by Qi Lu; Jialin Yu; Xiqiang Yang; Jiarong Wang; Lijia Wang; Yayin Lin; Lihua Lin

Book ID
118744231
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
490 KB
Volume
36
Category
Article
ISSN
0924-8579

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Screening for novel quorum-sensing inhib
Screening for novel quorum-sensing inhibitors to interfere with the formation of Pseudomonas aeruginosa biofilm
โœ Ding, X.; Yin, B.; Qian, L.; Zeng, Z.; Yang, Z.; Li, H.; Lu, Y.; Zhou, S. ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Society for General Microbiology ๐ŸŒ English โš– 742 KB

The objective of this study was to screen for novel quorum-sensing inhibitors (QSIs) from traditional Chinese medicines (TCMs) that inhibit bacterial biofilm formation. Six of 46 active components found in TCMs were identified as putative QSIs based on molecular docking studies. Of these, three comp