Amantadine increases aromatic 1L-amino acid decarboxylase mRNA in PC12 cells

Reciprocal regulation of the content of

Reciprocal regulation of the content of aromatic L-amino acid decarboxylase and tyrosine hydroxylase mRNA by NGF in PC12 cells

✍ X.-M. Li; J. Qi; A.V. Juorio; A.A. Boulton 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 86 KB

Aromatic l-amino acid decarboxylase (AADC) and tyrosine hydroxylase (TH) are involved in the synthesis of dopamine and other monoamine neurotransmitters, and their activities can be regulated by a number of physiological stimuli. An interesting finding has been that (2)-deprenyl and some other irrev