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Alzheimer's disease presenting as corticobasal syndrome

✍ Scribed by Pratap Chand; Jordan Grafman; Dennis Dickson; Keisuke Ishizawa; Irene Litvan

Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 90 KB
Volume: 21
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.21055

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✦ Synopsis

Abstract

A 60‐year‐old man presented with slowly progressive left hemi‐Parkinsonism, left hand apraxia, myoclonus, dystonia, visuospatial disturbances, and alien limb phenomenon, resembling corticobasal syndrome. Eight years later, neuropathology revealed features of Alzheimer's disease, with asymmetrical (right more than left) cortical tau burden with image analysis. The videotaped clinical features, neuropsychological aspects, and neuropathological correlates are presented and discussed. © 2006 Movement Disorder Society

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