✦ LIBER ✦

Alzheimer'S disease: Monoamines and spiperone binding reduced in nucleus basalis

✍ Scribed by D. Larry Sparks; William R. Markesbery; Dr John T. Slevin

Publisher: John Wiley and Sons
Year: 1986
Tongue: English
Weight: 338 KB
Volume: 19
Category: Article
ISSN: 0364-5134
DOI: 10.1002/ana.410190616

No coin nor oath required. For personal study only.

✦ Synopsis

This research was carried out during the tenure of a postdoctoral fellowship from the Muscular Dystrophy Association awarded to Dr Argov. We thank Dr N. R. M. Buist for his ongoing interest in this case and the support of his Muscular Dystrophy Association grant.

📜 SIMILAR VOLUMES

Loss of nucleus basalis neurons containi

Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer's disease

✍ Elliott J. Mufson; Shuang Y. Ma; Elizabeth J. Cochran; David A. Bennett; Laural 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 323 KB 👁 2 views

Recent studies indicate that there is a marked reduction in trkA-containing nucleus basalis neurons in end-stage Alzheimer's disease (AD). We used unbiased stereological counting procedures to determine whether these changes extend to individuals with mild cognitive impairment (MCI) without dementia

Down-regulation of trkA mRNA within nucl

Down-regulation of trkA mRNA within nucleus basalis neurons in individuals with mild cognitive impairment and Alzheimer's disease

✍ Yaping Chu; Elizabeth J. Cochran; David A. Bennett; Elliott J. Mufson; Jeffrey H 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 445 KB 👁 1 views

## Abstract Recent studies indicate that trkA expression is reduced in end‐stage Alzheimer's disease (AD). However, understanding the neuropathologic correlates of early cognitive decline, as well as the changes that underlie the transition from nondemented mild cognitive impairment (MCI) to AD, ar

Striatal monoamine terminals in Lewy bod

Striatal monoamine terminals in Lewy body dementia and Alzheimer's disease

✍ Sid Gilman; Robert A. Koeppe; Roderick Little; Hyonggin An; Larry Junck; Bruno G 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 88 KB 👁 2 views

Preservation of nucleus basalis neurons

Preservation of nucleus basalis neurons containing choline acetyltransferase and the vesicular acetylcholine transporter in the elderly with mild cognitive impairment and early Alzheimer's disease

✍ Gilmor, Michelle L.; Erickson, Jeffrey D.; Varoqui, H�l�ne; Hersh, Louis B.; Ben 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 473 KB 👁 2 views

Immunocytochemistry for choline acetyltransferase (ChAT) and the vesicular acetylcholine transporter (VAChT) was used to examine the expression of these linked cholinergic markers in human basal forebrain, including cases with early stages of Alzheimer's disease (AD). Previous neurochemical studies

Competition of congo red and thioflavin

Competition of congo red and thioflavin S binding to amyloid sites in alzheimer's diseased tissue

✍ A. Elhaddaoui; E. Pigorsch; A. Delacourte; S. Turrell 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 498 KB

Though the strong affinity of Congo red and thioflavin S for amyloid deposits has been known for a long time, the binding mechanism of these biological dyes to amyloid sites is still not understood. In the present work, the competition of these two dyes for binding in Alzheimer amyloid is investigat

Reduced CSF PLTP activity in Alzheimer's

Reduced CSF PLTP activity in Alzheimer's disease and other neurologic diseases; PLTP induces ApoE secretion in primary human astrocytes in vitro

✍ Simona Vuletic; Elaine R. Peskind; Santica M. Marcovina; Joseph F. Quinn; Marian 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 105 KB

## Abstract Phospholipid transfer protein (PLTP) plays a pivotal role in cellular lipid efflux and modulation of lipoprotein metabolism. PLTP is distributed widely in the central nervous system (CNS), is synthesized by glia and neurons, and is active in cerebrospinal fluid (CSF). The aims of this s