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Alzheimer’s disease and the ‘ABSENT’ hypothesis: mechanism for amyloid β endothelial and neuronal toxicity

✍ Scribed by Samir Roy; Arvi Rauk

Book ID
116742409
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
466 KB
Volume
65
Category
Article
ISSN
0306-9877

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## Abstract The extracellular accumulation of amyloid‐beta (Aβ) in neuritic plaques is one of the characteristic hallmarks of Alzheimer's disease (AD), a progressive dementing neurodegenerative disorder of the elderly. By virtue of its structure, Aβ is able to bind to a variety of biomolecules, inc