𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Alzheimer’s disease: amyloidβ-peptide antibody vaccine as plaque remover

✍ Scribed by Arun Kumar

Book ID
110637889
Publisher
Indian Academy of Sciences
Year
2000
Tongue
English
Weight
24 KB
Volume
25
Category
Article
ISSN
0250-5991

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Polypeptide conjugates comprising a β-am
Polypeptide conjugates comprising a β-amyloid plaque-specific epitope as new vaccine structures against Alzheimer's disease
✍ Marilena Manea; Gábor Mezö; Ferenc Hudecz; Michael Przybylski 📂 Article 📅 2004 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 243 KB

## Abstract Immunotherapeutic approaches designed to induce a humoral immune response have recently been developed for possible vaccination to the treatment of Alzheimer's disease (AD). Based on the identification of Aβ(4–10) (FRHDSGY) as the predominant B‐cell epitope recognized by therapeutically

The amyloid-β peptide and its role in Al
The amyloid-β peptide and its role in Alzheimer's disease
✍ Andrew B. Clippingdale; John D. Wade; Colin J. Barrow 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 334 KB

## Abstract Amyloid formation plays a central role in the cause and progression of Alzheimer's disease. The major component of this amyloid is the amyloid‐β (Aβ) peptide, which is currently the subject of intense study. This review discusses some recent studies in the area of Aβ synthesis, purifica

Diphenylpropynone derivatives as probes
Diphenylpropynone derivatives as probes for imaging β-amyloid plaques in Alzheimer’s brains
✍ Masahiro Ono; Hiroyuki Watanabe; Rumi Watanabe; Mamoru Haratake; Morio Nakayama; 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 428 KB

A new series of diphenylpropynone (DPP) derivatives for use in vivo to image β-amyloid (Aβ) plaques in the brain of patients with Alzheimer's disease (AD) were synthesized and characterized. Binding experiments in vitro revealed high affinity for Aβ (1-42) aggregates at a K(i) value ranging from 6 t