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Alzheimer β-amyloid precursor proteins display specific patterns of expression during embryogenesis

✍ Scribed by Manuel Sarasa; Vı&́ctor Sorribas; José Terrado; Salvador Climent; José M. Palacios; Guadalupe Mengod


Book ID
118601919
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
927 KB
Volume
94
Category
Article
ISSN
0925-4773

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✍ Hiroyuki Arai; Virginia M.-Y. Lee; Meridith L. Messinger; Barry D. Greenberg; Da 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 861 KB

Both neural and nonneural human tissues from patients with or without Alzheimer's disease (AD) were surveyed to detect the presence of the P-amyloid protein and its precursors. This was accomplished using polyclonal and monoclonal antibodies to epitopes in the 695 amino acid long p-APP (i.e., P-APPm