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Alzheimer disease: from abnormal phosphorylation of tau to neurofibrillary degeneration

✍ Scribed by Tuso, Philip; Moudgil, Asha; Hay, Jeffery; Goodman, David; Kamil, Elaine; Koyyana, RaQini; Jordan, Stanley C.


Book ID
124139493
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
153 KB
Volume
15
Category
Article
ISSN
0197-4580

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Mapping of neurofibrillary degeneration
✍ P. Vermersch; B. Frigard; A. Delacourte πŸ“‚ Article πŸ“… 1992 πŸ› Springer-Verlag 🌐 English βš– 905 KB

A biochemical mapping of neurofibrillary degeneration was performed in Brodmann areas of the brains of five patients with senile dementia of the Alzheimer type (AD). To quantify the degenerating process, we used an immunoblot method with antibodies directed against the abnormally phosphorylated tau