Astroglia-mediated effects of uric acid
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Yangzhou Du; Christopher P. Chen; Chia-Yi Tseng; Yuval Eisenberg; Bonnie L. Fire
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Article
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2007
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John Wiley and Sons
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English
β 575 KB
## Abstract Uric acid (UA) has been demonstrated to reduce damage to neurons elicited by oxidative stress. However, our studies utilizing cultures derived from embryonic rat spinal cord indicate that an astrogliaβmediated mechanism is involved in the effects of UA to protect neurons from glutamate