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Aluminum Chloride Pretreatment of Elastin Inhibits Elastolysis by Matrix Metalloproteinases and Leads to Inhibition of Elastin-Oriented Calcification

✍ Scribed by Michael Bailey; Hui Xiao; Matthew Ogle; Naren Vyavahare


Book ID
117021447
Publisher
American Society for Investigative Pathology
Year
2001
Tongue
English
Weight
371 KB
Volume
159
Category
Article
ISSN
0002-9440

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## Abstract Glutaraldehyde crosslinked bioprosthetic heart valves (BHVs) have two modalities of failure: degeneration (cuspal tear due to matrix failure) and calcification. They can occur independently as well as one can lead to the other causing co‐existence. Calcific failure has been extensively