Alumina-promoted fast solid-phase Michael addition of enamines with conjugated enones under microwave irradiation

✍ Scribed by Utpal Sharma; Utpal Bora; Romesh C Boruah; Jagir S Sandhu

• Book ID: 104232093
• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 112 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)02049-4

✦ Synopsis

A fast alumina-promoted solid-phase Michael addition of enamines to conjugated enones is described under microwave irradiation in high yields. The 1,5-diketo Michael adducts have been converted into a novel class of 1%,2%-diazepino(17,16-d%) steroids.